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Andronic Volkov
Andronic Volkov

HDWhen We First Met

The attainment of LLDAS is an important treatment goal for people affected with SLE, as it has been associated with protection from flares and damage accrual [13]. In this study, we analysed the characteristics of HDAS episodes which were defined by the first attainment of LLDAS after patients experienced HDAS. Our study sheds light on the heterogeneity of the duration of these HDAS episodes. Longer duration of HDAS episodes and multiple recurrent HDAS episodes were strong predictors for damage accrual. Many factors can determine the duration of an HDAS episode, but one important consideration was the baseline disease activity. Higher SLEDAI-2K at the onset of HDAS was associated with longer HDAS episodes, which in turn was associated with an increased likelihood of damage accrual.

HDWhen We First Met

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In late January, PIH/ZL began training the first 55 women and men as Pwojè Kore Fanmi HDAs. The HDAs will soon begin working in the countryside, providing services to families who have been targeted as needing assistance. In past models, community agents would provide similar services to all families. This new model tailors services, addressing each family's specific needs. The HDAs will return every month through September for further training and support.

Yes, NotSoTechnical. The FileVault bug is one that seems fairly known about. I saw a number of threads discussing it within the first few pages, and the only solutions seem to have been wait for Apple to come up with a fix or reinstall OS X.

In a clinical trial, Papadoupoulos and coleagues (2005) assessed the effectiveness of a novel regimen of tandem HDC (THDC) with autologous stem cell transplantation in the treatment of patients with poor risk lymphoma. A total of 41 patients (median age of 40 years, range of 15 to 68 years) with poor risk non-Hodgkin's lymphoma and HD were enrolled. Tandem HDC consisted of melphalan (180 mg/m2) and escalating dose mitoxantrone (30 to 50 mg/m2) (MMt) for the first conditioning regimen, and thiotepa (500 mg/m2), carboplatin (800 mg/m2), and escalating dose etoposide phosphate (400 to 850 mg/m2), (ETCb) as the second regimen. In all, 31 patients (76 %) completed both transplants, with a median time between transplants of 55 days (range of 26 to 120 days). The maximum tolerated dose was determined as 40 mg/m2 for mitoxantrone and 550 mg/m2 for etoposide phosphate. The overall toxic death rate was 12 %. Following HDC, 10 of 24 evaluable patients (42 %) were in complete remission. The 2-year OS and EFS is 67 % (95 % confidence interval (CI): 52 % to 81 %) and 45 %, (95 % CI: 29 % to 61 %) for the 41 patients enrolled; and 69 % (95 % CI: 525 % to 586 %) and 48 % (95 % CI: 30 % to 67 %) for the 31 patients completing both transplants. This THDC regimen is feasible but with notable toxicity in heavily pre-treated patients; its role in the current treatment of high-risk lymphoma remains to be determined.

Chopra and associates (1993) reported the results of 155 patients with relapsed or resistant HD who were treated with HDC followed by ABMR. At the time of transplant, 46 patients were primarily refractory to induction therapy, 7 were good partial responders, and 52 were in first relapse, 37 in second relapse, and 13 in third relapse. At 3 months 43 (28 %) patients were assessed as complete responders. Seventy-two (46 %) patients were assessed to have partial responses (PR). Twenty-four patients (16 %) showed no response or progression. At 6 months, 53 patients were assessed as complete responders. Thirteen patients in PR at 3 months had achieved a CR by 6 months, this occurring in 8 patients after radiotherapy to residual masses, and 5 patients without any further treatment indicative of slow resolution of their tumor masses. Fifty-one patients still had non-progressive disease with persistent CT abnormalities, 26 patients had relapsed with progressive disease, and 8 patients had died of progressive HD. Overall, 104 of 155 (67 %) had a good response to ABMR. By 6 months, there were 17 procedure-related deaths. The actuarial OS at 5 years was 55 %, with a progression-free survival (PFS) of 50 %. The authors found that patients undergoing ABMR in second and third relapse were faring significantly better than patients in first relapse and primary refractory disease.

In a review, Mink and Armitage (2001) stated that ASCT has proven to be beneficial in selected patients with HD. Transplantation appeared to increase EFS in patients who failed to enter complete remission with initial therapy. When a patient relapses after a complete remission, transplantation is probably the best option and particularly so if the remission lasted less than 1 year. Transplantation as part of primary therapy for very high-risk patients may be beneficial, but is not standard therapy at this time. Lazarus et al (2001) reviewed data from the Autologous Blood and Marrow Transplant Registry (n = 414) to determine relapse, disease-free survival, OS, and prognostic factors in patients with relapsed HD. They concluded that autologous hematopoietic stem cell transplantation (autotransplantation) should be considered for patients with HD in first relapse or second remission.

DG: I would like to add that for me I was interested in an ambiguity staying throughout in terms of their relationship. Had they met before? Was this their first encounter, series of encounters, or was this a planned rendez-vous?

Early in your tenure, everyone, even those you have worked with for years, is forming their first impression of you as the CEO. Getting your first impressions right will send strong messages about how you intend to lead differently (from the previous CEO, as well as versus how you have led in previous roles) and the renewal opportunity you see for the organization. Applying the following four principles will go a long way to ensuring that your first impressions are positive:

Metropolitan Opera Live in HD (also known as The Met: Live in HD) is a series of live opera performances transmitted in high-definition video via satellite from the Metropolitan Opera in New York City to select venues, primarily movie theaters, in the United States and other parts of the world. The first transmission was of a condensed English-language version of Mozart's The Magic Flute on December 30, 2006. Many of the video recordings are later rebroadcast via public television as part of the Great Performances at the Met series, and most are made available for streaming at Met Opera on Demand.

The first season included seven theatres in Britain, two in Japan and one in Norway. After its successful launch, several other countries joined for the second season and 100 screens were added, selling an additional 20,000 tickets.[citation needed] These included cinemas in Belgium, France, Germany, Italy, and Spain.

Movie and radio broadcast revenue increased for the Met from about $5 million in 2006, Live in HD's first year, to $22 million in 2008, with Live in HD contributing the bulk of the growth.[9] For the 2009/10 season, the Met spent about $12 million in production and received about half of the $47 million box-office gross. After paying royalties to its cast and crew, the Met earned a $8 million profit.[10] The Met's Live in HD revenue for the 2012/13 season was $34.5 million.[11]

The first showing on December 15, 2007, Gounod's Roméo et Juliette, was seen on 477 screens and sold an estimated 97,000 tickets. The series continued by featuring seven more of the Met's productions following Roméo et Juliette and ending with La fille du régiment on April 26, 2008.[24]

Research design and methods: A retrospective cohort was constructed using administrative data from the national HDA database, PSCs for Ontario (population 11 million), and registries carrying demographics and vital statistics. All HDAs and PSCs bearing a diagnosis of diabetes (ICD9-CM 250) were selected for 1991-1999. Two previously reported algorithms for identification of diabetes were applied as follows: "1-claim" (any HDA or PSC showing diabetes) and "2-claim" (one HDA or two PSCs within 2 years showing diabetes). Incident cases were defined as individuals who met the criteria for diabetes for the first time after at least 2 years of observation. For validation, diagnostic data abstracted from primary care charts (n=3,317) of 57 randomly selected physicians were linked to the administrative data cohort, and sensitivity and specificity were calculated.

This is a known issue, as "Start Recording Automatically" does start the cloud recording as soon as the first participant enters the meeting. There are a few ways to work around this:1. Turning off Automatic Recording, which may not be the best option as you would have to remember to manually start recording each time.2. Turning off "Allow Participants to Join at Any time" and enabling the Waiting Room. This will keep students from entering the meeting until you join, which will start recording.3. Editing the recorded video after the recording is published. We recommend Zoom cloud recordings to be uploaded to Panopto video management, and Panopto has editing features that will let you trim the start of the video before the actual meeting begins.

One general question: Would it be better to run the switch in aggregation mode, with all VLANs OpenFlow-controlled, and implement the first type of VLAN by running a learning-switch controller on the control node? Nick is probably best positioned to talk about the pros and cons of this approach, but we weren't sure if it had been considered and rejected, or was stillon the table, or not really considered yet, or what.

Toshiba feels that with large flat-panels sales in North America poised to tick upward by the beginning of 2015, this is the perfect opportunity to educate rather than thrust 4K Ultra HD down consumers throats with no content available and what is likely to be a high asking price for first-generation products. 041b061a72


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